Inositol, sometimes referred to as vitamin B8, is actually not a vitamin, it’s a form of sugar with several important functions, such as being a major component of cell membranes - this is important to note when understanding how it helps insulin sensitivity.

How Inositol Reverses Insulin Resistance
Insulin acts as the key to the cells of your body. It’s as if the cells of your body each have a door that’s locked. All of the nutrients and energy that's in your bloodstream, which needs to get into the cells to power you as a human, cannot without insulin.

With a condition such as insulin resistance, the doors on your cells are basically rusted shut, this leads to a buildup of energy (sugar) in your bloodstream as well as insulin, a situation called hyperinsulinemia.

Inositol can act as a secondary messenger, or ‘door’ for your cells. This allows a healthy amount of nutrients from your bloodstream into the cells that need it. This means a healthy level of blood sugar and insulin in your bloodstream.

The Benefits of Inositol Include:
 - Aid in weight loss
 - Boost ovulation and fertility
 - Improve energy levels
- Reduce sugar cravings
- Lowers testosterone levels (acne, hair loss & hair growth)

What Is The Evidence Showing?

One study noted that 4 grams of inositol and 400 mcg of folic acid taken daily for 3 months induced ovulation in 62% of treated women. Compared to just 12% of women who only took a straight folic acid supplement without the inositol

In a 12 month long clinical study of 80 women with metabolic syndrome, 2 grams of inositol taken twice daily and resulted in reduced blood triglyceride levels by 34% and total cholesterol by 22%.

In a study that looked into metformin vs. inositol & folic acid treatment for pregnancy, metformin achieved an 18% pregnancy rate over a 6 month period while in the inositol & folic acid group, 30% of women managed to fall pregnant naturally.

A study looking into the effects of metformin (1500mg daily) vs. inositol (4 gram daily) on improving insulin sensitivity. The myo-inositol outperformed metformin when it came to improving insulin sensitivity and reducing testosterone levels, hirsutism, and markers of inflammation.

How Much Should You Take?
In terms of how much inositol you should take, I recommend my client starting at 3 - 4 grams per day, or a teaspoon - to test your response to it. I know many women who take up to 6 grams a day without any side effects. 

Benefits

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